Perfluorooctanesulfonic acid (PFOS), or perfluorooctane sulfonate is a compound that was primarily made by 3M in the US. Under advisement by the Environmental Protection Agency is is no longer produced for products in the United States. Before 2000, it was used in foam and as fire retardents as well, as for Scotchguard for carpets. The chemical has also been found in wildlife at levels that may effect health. (Wipedia)
In recent studies, it has demonstrated some health effects but the studies have been considered as biased and somewhat controversial. A new study again shows there may be effects on the immune system. Th results show that " PFOS exposure can alter some inflammatory processes, which could potentially lead to misdirected inflammatory responses." In a previous 2010 study, results showed substantial elevations in immune parameters with LPS.(Dong)
In individuals who already may be susceptible to altered immune function, this may have a negative impact on health. Mixed exposures may augment the inflammatory response and immune changes.
Mollenhauer, M. A., Bradshaw, S. G., Fair, P. A., McGuinn, W. D. & Peden-Adams, M. M. Effects of perfluorooctane sulfonate (PFOS) exposure on markers of inflammation in female B6C3F1 mice. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 46, 97-108 (2011). URL http://dx.doi.org/10.1080/10934529.2011.532418.
Dong, G.-H. H. et al. Subchronic effects of perfluorooctanesulfonate exposure on inflammation in adult male C57BL/6 mice. Environmental toxicology (2010). URL http://dx.doi.org/10.1002/tox.20642.
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Perfluorooctanesulfonic acid. Wipedia. Retrieved on December 21, 2010. http://en.wikipedia.org/wiki/Perfluorooctanesulfonic_acid